ANTAGONISTIC ACTIVITY OF ISOLATED PROBIOTICS AGAINST ESCHERICHIA COLI ESBL

  • Douglas Zarur Universidade Alto Vale do Rio do Peixe
  • Vilmair Zancanaro Universidade Alto Vale do Rio do Peixe- UNIARP
  • Fernanda H. Lorenzon Pontifícia Universidade Católica do Paraná- PUC-PR
  • Emyr Hiago Bellaver Universidade Alto Vale do Rio do Peixe- UNIARP http://orcid.org/0000-0002-7169-1000

Resumo

Potentially all microorganisms are able to synthesize several substances in vitro with inhibitory activity for themselves or other microorganisms, producing bactericidal or bacteriostatic effects. The objective of this work was to establish the bacterial growth antagonistic properties of Escherichia coli ESBL by Lactobacillus casei strain Shirota, Bifidobacterium animalis DN173010, isolated of commercial probiotic products, and Kefir grain by the overcoated agar method. Analysis of the results allowed to gauge halos of 7.1 ± 2 mm inhibition of growth by L. casei strain Shirota and 6.3 ± 2 mm by B. animalis DN173010, Kefir grains did not produce inhibition halos against the multiresistant strain. The bacterial growth inhibition activity can be justified by the competition of nutrients from the medium and/or by the secretion of bacteriocins, protein or peptidic compounds ribosomally synthesized in the primary metabolism with antagonistic activity and because proteins are expected to behave differently on certain target microorganisms and culture conditions, and the production of these compounds by the Kefir grains cannot be excluded.

Biografia do Autor

Douglas Zarur, Universidade Alto Vale do Rio do Peixe
Acadêmico do curso de Farmácia da Universidade Alto Vale do Rio do Peixe- UNIARP
Vilmair Zancanaro, Universidade Alto Vale do Rio do Peixe- UNIARP
Farmacêutica Bioquímica. Mestre em Ciência e Biotecnologia. Professora do núcleo de Ciências da Saúde da Universidade Alto Vale do Rio do Peixe- UNIARP.
Fernanda H. Lorenzon, Pontifícia Universidade Católica do Paraná- PUC-PR
Especialista em microbiologia. Pontifícia Universidade Católica do Paraná- PUC-PR
Emyr Hiago Bellaver, Universidade Alto Vale do Rio do Peixe- UNIARP
Biomédico patologista clínico e microbiologista. Mestre em Ciência e Biotecnologia. Professor do núcleo de Ciências da Saúde da Universidade Alto Vale do Rio do Peixe- UNIARP.
Publicado
20-12-2017
Como Citar
Zarur, D., Zancanaro, V., Lorenzon, F. H., & Bellaver, E. H. (2017). ANTAGONISTIC ACTIVITY OF ISOLATED PROBIOTICS AGAINST ESCHERICHIA COLI ESBL. Anais eletrônicos Do International Symposium on Science and Biotechnology. Recuperado de https://portalperiodicos.unoesc.edu.br/ISSB/article/view/16118